ODCs

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1 OMIM reference -
1 associated gene
13 signs/symptoms

PROTEIN INTERACTIONS: 2

1 OMIM reference -
4 associated genes
No signs/symptoms info

Hypothyroidism due to TSH receptor mutations

Myelofibrosis with myeloid metaplasia


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TSHR TSHR	(0.73) (0.65)	JAK2 CALR

Citations in the biomedical literature:

Hypothyroidism due to TSH receptor mutations		Myelofibrosis with myeloid metaplasia
	Synonym(s): (no synonyms)		Synonym(s): - Agnogenic myeloid metaplasia - Idiopathic myelofibrosis - Myelosclerosis with myeloid metaplasia - Primary myelofibrosis

	Classification (Orphanet): - Rare endocrine disease - Rare genetic disease		Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Neoplasms -

	Epidemiological data: (no data available)		Epidemiological data: (no data available)

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references

Hypothyroidism due to TSH receptor mutations
	Very frequent - Abnormal cry / voice / phonation disorder / nasal speech - Absent / hypotonic / flaccid abdominal wall muscles - Anomalies of skin, subcutaneous tissue and mucosae - Constipation - Face / facial anomalies - Failure to thrive / difficulties for feeding in infancy / growth delay - Hepatitis / icterus / cholestasis - Hypothyroidy - Hypotonia - Large fontanelle / delayed fontanelle closure - Macroglossia / tongue protrusion / proeminent / hypertrophic - Sleep and vigilance disorders - Umbilical hernia
Myelofibrosis with myeloid metaplasia
(no data available)